Multivesicular Structures in Proliferating Fibroblasts of Rabbit Ovarian Follicles during Ovulation
نویسنده
چکیده
During ovulation and luteinization in mammals a portion of the ovarian tissue undergoes extensive remodeling. The thecal framework of a mature follicle is degraded and disrupted as the ovum is released. Immediately following ovulation the fibroblasts rapidly undergo functional reorientation (a) to initiate healing at the point of rupture and (b) to meet the changing requirements for support of the proliferating lutein cells . These features make the ovulating follicle a useful model for studying collagen resorption and synthesis . Prior to ovulation in the rabbit the follicle wall loses tensile strength (1), and the dense collagenous tissue in the thecal layers dissociates (2) . Recent data reveal that follicular fibroblasts produce multivesicular structures which protrude from the cell surface and appear to digest the ground substance surrounding them .'
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ورودعنوان ژورنال:
- The Journal of Cell Biology
دوره 48 شماره
صفحات -
تاریخ انتشار 1971